Abstract The fatal motor neuron (MN) disease Amyotrophic Lateral Sclerosis (ALS) is characterized by progressive MN degeneration. Phrenic MNs (phMNs) controlling the activity of the diaphragm are prone to degeneration in ALS. leading to death by respiratory failure. Understanding of the mechanisms of phMN degeneration in ALS is limited. https://www.foldlyers.shop/product-category/fme-f-type-n-type/