Approximately one third of individuals with major depressive disorder (MDD) do not respond to antidepressant treatments; but what does treatment-resistant depression (TRD) mean. With this article. I aim to provide an overview of the clinical and operational criteria currently used to define TRD. highlighting core gaps in knowledge and open questions to be addressed in order to drive f... https://yeswellneses.shop/product-category/childrens-digestive-care/