There is currently a lack of reliable methods and strategies to probe the deubiquitinating enzyme UCHL3. Current small molecules reported for this purpose display reduced potency and selectivity in cellular assays. To bridge this gap and provide an alternative approach to probe UCHL3. our group has carried out the rational design of ubiquitin-variant activity-based probes with selecti... https://ashleyshomestores.shop/product-category/extension-kit/